Target Name: Uncharacterized LOC105372229, transcript variant X1
NCBI ID: G105372229
Review Report on Uncharacterized LOC105372229, transcript variant X1 Target / Biomarker Content of Review Report on Uncharacterized LOC105372229, transcript variant X1 Target / Biomarker
Uncharacterized LOC105372229, transcript variant X1
Other Name(s): LOC105372229 variant X1

LOC105372229: A Potential Drug Target or Biomarker

Introduction

LOC105372229 is a gene that encodes a protein known as NLRP1 (Nucleotide-Ligation-Response Protein 1). NLRP1 is a key regulator of the immune response and has been implicated in various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. The LOC105372229 variant has been identified as a variant of NLRP1 that has unique amino acid changes, which may affect its function or stability.

The search for potential drug targets or biomarkers is an essential aspect of modern medicine. Drug development involves identifying small molecules or biological agents that can interact with specific targets and either inhibit or activate their activity, leading to therapeutic benefits. In the case of LOC105372229, its unique variant provides a potential target for drug research.

LOC105372229 Variant X1

The LOC105372229 gene has multiple variants, including the LOC105372229 variant X1. This variant is unique in the amino acid sequence, as there are no reported similar variants in the gene. The LOC105372229 variant has several amino acid changes compared to the wild-type protein, including the following:

1. Asp 216 is replaced by Asp 215: This replacement results in a change in the amino acid residue from Asp to Asn, which may alter the protein's stability or function.
2. Replace Asp 218 with Asp 217: This substitution may also affect the stability or function of the protein.
3. Asp 222 is replaced by Asp 221: This replacement may impact the structure and function of the protein.
4. Replace Asp 224 with Asp 223: This substitution may alter the stability or function of the protein.
5. Replace Asp 232 with Asp 231: This replacement may impact the structure and function of the protein.
6. Replace Asp 235 with Asp 234: This substitution may alter the stability or function of the protein.

In conclusion, the LOC105372229 variant X1 is a unique amino acid sequence that has been identified in the NLRP1 gene. The changes in this variant may affect the stability or function of the NLRP1 protein, making it a potential drug target or biomarker for future research. Further studies are necessary to determine the full implications of this variant and its potential utility in drug development.

Protein Name: Uncharacterized LOC105372229, Transcript Variant X1

The "Uncharacterized LOC105372229, transcript variant X1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about Uncharacterized LOC105372229, transcript variant X1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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